Avera Creighton Hospital has a 30-bed capacity and offers numerous services including: laboratory, X-ray, recovery room, intensive care unit, inhalation therapy, and swing beds. Home health, outpatient surgery, physical and respiratory therapy, prenatal classes, social services, ultrasounds, and CAT scans are also offered.

The hospital also has a number of specialty clinics including: EEG and nerve conduction study, Knox County Immunization Clinic, orthopedics, OB-GYN, vascular, podiatry, cardiology, urology, mammograms, pulmonology clinics, mental health clinics, MRI, and ear, nose and throat services. Creighton Area Health Services has four facilities to serve the residents of Northeast Nebraska which includes a hospital, two medical clinics, and a nursing home. They are located 45 miles from Norfolk, NE and 35 miles from Yankton, SD.